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78 Notably, female subjects on GLP-1 medicines had a higher risk of major depressive disorder (216% elevated risk [HR: 3.16, 95% CI 2.983.34]) and black patients had the highest risk of anxiety (137% elevated risk [HR: 2.37, 95% CI: 2.252.50]) compared to non-users

Reduced glutathione levels can lead to increased oxidative stress and impaired detoxification, while decreased methylation can lead to a range of health issues, including mood disorders, cognitive dysfunction, and cancer

A.et al (1999)

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Not only do the effects on BP differ between acute and chronic administration methods, it is also seemingly species-dependent